exp opcode increased, impacts gas estimation and optimization.returndatacopy, returndatasize and staticcall available in assembly.
staticcall opcode used when calling non-library view or pure functions, which prevents the functions from modifying state at the EVM level, this even applies to invalid type conversions.
Ability to access dynamic data returned from function calls.
revert opcode introduced, revert() will not waste gas.create2, extcodehash, shl, shr and sar are available in assembly.
Bitwise shifting operators use shifting opcodes (shl,shr,sar), requiring less gas.chainid and selfbalance are available in assembly.SLOAD, *CALL, BALANCE, EXT* and SELFDESTRUCT increased. The compiler assumes cold gas costs for such operations. This is relevant for gas estimation and the optimizer.